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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Pathophysiology. 2012 May 26;20(1):71–84. doi: 10.1016/j.pathophys.2012.03.003

Fig. 2.

Fig. 2

Stage-dependent pathology of EAE induced with MOG92-106. (a, c) In RR-EAE, intense CD3+ T cell infiltration was observed around vessels (v) with mild demyelination. (b, d) In progressive EAE, T cell infiltration was sparse around vessels (v), despite large areas of demyelination (arrowheads). UV irradiation can alter the disease course from RR-EAE to SP-EAE in SJL/J mice sensitized with MOG92-106. PP-EAE was induced in A.SW mice sensitized with MOG92-106. (a, b) Luxol fast blue stain. (c, d) CD3 immunohistochemistry. Magnification × 70.