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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Neurochem Int. 2012 Jun 16;61(3):389–396. doi: 10.1016/j.neuint.2012.06.003

Figure 5.

Figure 5

Effect of synaptic glutamate accumulation on ATP abundance. Incubation of cultured neurons with glutamate transporter inhibitor TBOA caused a marked reduction in ATP levels, which was blocked by receptor antagonist cocktail (AC). Co-application of TBOA and glutamate reduced ATP to a level similar to that by either glutamate or TBOA alone, suggesting a saturation by a single treatment, or a shared cellular process triggered by global and synaptic glutamate stimulation. *P<0.05, student’s t test.