Table 2.
Characteristics and health status of infertile and fertile women who conceived a singleton pregnancy
| Variable | Infertile with treatment n=542 | Infertile without treatment n=441 | Fertile n=1008 | p-value |
|---|---|---|---|---|
| Maternal Age Mean ± SD | 36.34 ± 4.9 | 35.25 ± 4.7 | 32.87 ± 5.1 | <.0001 |
| Body Mass Index (BMI) Mean ± SD | 24.669 ± 5.4 | 24.888 ± 5.5 | 24.19 ± 5.0 | .06 |
| Nulliparous | 322 (59.7%) | 265 (39.8%) | 590 (41.5%) | <.0001 |
| Nulligravida | 157 (29.0%) | 85 (19.3%) | 226 (22.4%) | .001 |
| Chronic hypertension | 8 (1.5%) | 3 (0.7%) | 12 (1.2%) | .50 |
| Diabetes prior to pregnancy | 5 (0.9%) | 5 (1.1%) | 4 (0.4%) | .23 |
| Heart disease prior to pregnancy | 3 (0.6%) | 3 (0.7%) | 3 (0.3%) | .56 |
| Obesity prior to pregnancy | 31 (5.8%) | 10 (2.3%) | 43 (4.3%) | .03 |
| Pregnancy-induced hypertension | 35 (6.8%) | 25 (6.0%) | 63 (6.3%) | .86 |
| Gestational diabetes | 51 (9.8%) | 22 (5.1%) | 87 (8.7%) | .03 |
| Excess weight gain during pregnancy | 2 (0.4%) | 3 (0.7%) | 7 (0.7%) | .72 |
| Smoking during pregnancy | 9 (1.9%) | 8 (2.1%) | 65 (6.8%) | <.0001 |
| Alcohol during pregnancy | 35 (7.6%) | 50 (13.4%) | 113 (12.1%) | .01 |
| Intra-uterine growth restriction (IUGR) | 19 (3.5%) | 11 (2.5%) | 16 (1.6%) | .05 |
| Small for gestational age (SGA) | 14 (2.7%) | 9 (2.1%) | 11 (1.1%) | .07 |
| Sepsis | 9 (1.7%) | 6 (1.4%) | 10 (1.0%) | .49 |
| Fetal or neonatal death | 9 (2.0%) | 4 (1.1%) | 7 (0.8%) | .17 |
| Preterm (<37 weeks) | 42 (8.1%) | 29 (6.8%) | 65 (6.6%) | .54 |
| LBW(<2500 g) | 56 (10.8%) | 37 (8.6%) | 63 (6.4%) | .01 |