Table 1.
Demographic characteristics of the study groups
| Characteristic | Control Group (n=36) | EPO-α Group (n=36) | P Value |
|---|---|---|---|
| Donor factors | |||
| age (yr) | 41±17 | 39±17 | 0.63 |
| men/women (%) | 56/44 | 44/56 | 0.30 |
| ECD kidney (%) | 22 | 11 | 0.21 |
| death from CVA (%) | 39 | 19 | 0.07 |
| terminal urine output (ml/hr) | 159±151 | 167±147 | 0.83 |
| terminal serum creatinine (mg/dl) | 1.18±0.90 | 1.14±0.85 | 0.84 |
| pressor use (%) | 67 | 86 | 0.05 |
| Recipient factors | |||
| age (yr) | 56±13 | 58±11 | 0.53 |
| men/women % | 53/47 | 56/44 | 0.81 |
| African Americans (%) | 14 | 19 | 0.53 |
| body mass index (kg/m2) | 28.3±6.4 | 27.8±5.4 | 0.71 |
| diabetes mellitus (%) | 56 | 47 | 0.48 |
| hypertension (%) | 92 | 94 | 0.64 |
| coronary artery disease (%) | 36 | 25 | 0.31 |
| previous dialysis (%) | 89 | 72 | 0.07 |
| previous transplant (%) | 22 | 17 | 0.55 |
| previous ESA use (%) | 86 | 69 | 0.09 |
| recent PRA (%) | 1.7±8.8 | 3.3±15.3 | 0.66 |
| HLA mismatch | 3.6±1.4 | 3.2±1.6 | 0.36 |
| Transplant-related factors | |||
| cold ischemia time (hr) | 26.3±8.0 | 24.1±6.1 | 0.21 |
| warm ischemia time (min) | 14.2±13.2 | 16.3±16.3 | 0.62 |
| lowest systolic BP in operating room (mmHg) | 101±17 | 98±11 | 0.31 |
Data expressed with plus/minus sign are the mean ± SD. EPO, erythropoietin; ECD, expanded-criteria donor; CVA, cerebrovascular accident; ESA, erythropoietic stimulating agent; PRA, panel-reactive antibody.