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. 2012 Jun 28;7(9):1481–1489. doi: 10.2215/CJN.13041211

Figure 2.

Figure 2.

Kidney injury molecule-1 (KIM-1) and IL-8 mRNA expression levels in donor kidney biopsies. Box plots show the minimum to maximum and 25th, 50th (median), and 75th percentiles for levels of mRNA for KIM-1 (A) and IL-8 (B) in biopsies from living (n=14) and deceased donor kidneys (n=11) after cold ischemia and reperfusion. In the biopsies taken after both cold storage and reperfusion, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) -normalized, log-transformed mRNA levels of KIM-1 and IL-8 were significantly higher in the deceased than living donor kidneys. The mRNA expression levels of KIM-1 and IL-8 did not significantly change after reperfusion in the deceased donor kidneys in contrast to the living donor kidneys (P=0.02 and P<0.01, respectively). Because of shortage of material, the mRNA levels of KIM-1 could not be tested in four biopsies.