Table 3.
Association between prescription patterns and achievement in target levels of phosphorus and calcium
| Prescription Pattern | ACa (pg/ml) | Proportionb (%) | PDc | 95% CI | ||
|---|---|---|---|---|---|---|
| Cinacalcet | VDRA | |||||
| Phosphorus (4026 sets) | ||||||
| Not | Decreased | −0.29 | 64.0 | 0.03 | −0.02 to 0.07 | |
| Not | Stable | −0.12 | 60.9 | Reference | ||
| Not | Increased | −0.01 | 61.6 | 0.00 | −0.03 to 0.04 | |
| Starting | Decreased | −0.82 | 72.5 | 0.12 | 0.04–0.20 | |
| Starting | Stable | −0.49 | 61.2 | 0.03 | −0.02 to 0.09 | |
| Starting | Increased | −0.35 | 67.4 | 0.07 | 0.00–0.15 | |
| Calcium (4027 sets) | ||||||
| Not | Decreased | −0.14 | 62.6 | 0.01 | −0.03 to 0.05 | |
| Not | Stable | 0.13 | 65.5 | Reference | ||
| Not | Increased | 0.32 | 65.4 | −0.02 | −0.06 to 0.01 | |
| Starting | Decreased | −0.69 | 65.7 | 0.09 | 0.01–0.17 | |
| Starting | Stable | −0.35 | 69.3 | 0.08 | 0.02–0.14 | |
| Starting | Increased | −0.16 | 60.3 | 0.03 | −0.05 to 0.11 | |
VDRA, vitamin D receptor activator; AC, absolute change; PD, proportion difference; 95% CI, 95% confidence interval; iPTH, intact parathyrpid hormone.
a
Means of AC between reference and outcome visits.
b
Proportions of patients with achievement of target levels.
c
Adjusted for age, sex, dialysis duration, intact PTH levels, phosphorus levels, calcium levels, use of calcium- or non–calcium-based phosphate binders, single-pool Kt/V, and dialysate calcium.