Table 2.

Associations of rs7903146 with diabetes-related quantitative traits

Trait	CC/CT/TT	CC	CT	TT	p value	p valuea	p valueb
FPG	1060/893/223	5.52±0.82	5.57±1.09	5.77±1.33	0.013	0.008	0.160
Mean FPG	1172/1036/258	5.36±0.85	5.51±1.29	5.59±1.22	0.003	0.002	0.570
2 h plasma glucose	403/347/75	6.93±2.46	7.33±2.85	8.22±3.16	0.002	0.005	0.040
HbA1c	973/831/200	5.46±0.59	5.54±0.78	5.62±0.81	0.026	0.021	0.210
Proinsulin	1007/854/215	14.21±12.15	14.79±13.0	15.87±11.27	0.043	0.010	0.080
Fasting insulin	1036/879/221	89.52±48.9	85.8±52.86	81.84±44.64	0.005	0.004	0.200
HOMA-IR	1036/879/221	3.8±2.58	3.7±2.98	3.63±2.34	0.059	0.063	0.240
Gutt’s ISI	391/341/75	22.15±7.18	21.77±7.51	19.22±6.72	0.043	0.066	0.150

Association between genotype at SNP rs7903146 and glycaemic traits using an additive genetic model. The genotype counts are listed next to each quantitative trait

The minor allele frequency is 0.31 and is based on data from Framingham unrelated participants

All quantitative trait values are crude means ± SD, with all p values adjusted for sex, age, and age², and further adjusted for either

^aBMI or

^bproinsulin/insulin ratio

Mean FPG, FPG averaged over examinations 3 to 7