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. Author manuscript; available in PMC: 2012 Aug 30.

Published in final edited form as: Gut. 2010 Oct 22;60(4):449–455. doi: 10.1136/gut.2010.226860

Table 2.

Cytokine Production by Cultured Peripheral Blood and Lamina Propria Monocytes

Responder		Peripheral Blood		Lamina Propria
	pg/mL	Pre	Post	Pre	Post
T cell Stimulation	IL-13	594 ± 327	265 ± 108	690 ± 99^*	297 ± 58^*
	IL-10	523 ± 176	528 ± 178	139 ± 58	128 ± 53
	IFN-©	4001 ± 1416	4955 ± 2334	1003 ± 185	1438 ± 210
	IL-4	114 ± 48	119 ± 53	102 ± 41	30 ± 10
	IL-17	39 ± 17	25 ± 4^#	8 ± 2⁺	6 ± 1^{^}
Macrophage Stimulation	IL-6	42466 ± 4982^¶	58063 ± 10605	1644 ± 147	1703 ± 265
	TNF-α	3439 ± 408	3250 ± 435	1012 ± 172	755 ± 220
	IL-12	279 ± 173	196 ± 70	33 ± 10	67 ± 25
Nonresponder
T cell Stimulation	IL-13	350 ± 116	393 ± 164	542 ± 83	510 ± 39
	IL-10	976 ± 491	574 ± 206	229 ± 119	437 ± 236
	IFN-©	1770 ± 599	2587 ± 1685	1688 ± 647	2700 ± 1455
	IL-4	116 ± 69	53 ± 35	78 ± 69	24 ± 22
	IL-17	191 ± 164	86 ± 27^#	70 ± 38⁺	70 ± 34^{^}
Macrophage Stimulation	IL-6	133177 ± 35259^¶	117952 ± 35883	1861 ± 836	5125 ± 3524
	TNF-α	5298 ± 1778	4429 ± 1278	885 ± 455	1346 ± 456
	IL-12	165 ± 68	86 ± 30	26 ± 6	20 ± 13

^*

p=0.01 Resp LP T cell IL-13 pre vs post

^#

p=0.006 PB Post T cell IL-17 Resp vs Nonresp

⁺

p=0.039 LP Pre T cell IL-17 Resp vs Nonresp

^{^}

p=0.017 Post LP T cell IL-17 Resp vs Nonresp

^¶

p=0.006 PB Pre Mac/APC IL-6 Resp vs Nonresp