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Schematic of the potential effects of modulating QscR and LasR receptor activities in P. aeruginosa. A) Normal receptor function: QscR negatively regulates LasR and provides a limit on virulence factor production. B) Increased QscR activity decreases LasR activity. C) Decreased QscR activity increases LasR activity. D) Simultaneous increase or decrease in QscR and LasR activities might show no net change in virulence factor production.
