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Administration of PGRN reduced the LPS-induced lung permeability. Groups of mice were treated as described above and then the total protein (a), albumin (b), and IgM (c) in BAL fluid were determined at day 3 after LPS challenge. Data are represented as mean ± standard deviation of one experiment consisting of three replicates. Experiments were performed in triplicate. *P < 0.05.
