Figure 5.

Administration of PGRN ameliorated the histopathology changes of lung in LPS-ALI mice. Groups of mice were treated as described above and then histological evaluation of therapeutic potential of PGRN on LPS-induced lung injury in mice was analyzed at day 3 after LPS challenge. (a) Representative images of hematoxylin and eosin stained lung sections from four experimental groups. (b) Lung injury score was determined. Data are represented as mean ± standard deviation of one experiment consisting of three replicates. *P < 0.05.