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Protease inhibitors partially prevented drug-induced cell detachment. (a) Antiproliferative effect of short-term (72 hours) exposure to PMSF and marimastat on A549 lung cancer cells. (b) Antiproliferative effect of PMSF and marimastat alone or in combination with M : SO on A549 lung cancer cells. (c) PMSF and marimastat prevented M : SO-induced cell detachment.
