Fig. 2.
Effect of αKG/MAL on the mean arterial blood pressure (MAP) during kidney I/R in rats. Anesthetized rats were subjected to bilateral kidney ischemia (I; 40 min) and subsequent reperfusion (R; 240 min). During the periods indicated (gray areas), αKG/MAL was infused at 0.0095 mmol·kg−1·min−1 each. Normoxic and I/R control group animals received only 0.9% NaCl solution (5 ml·kg−1·h−1). Values are means ± SE of 6 rats/group. For experimental details see Fig. 1. *P < 0.05 vs. normoxic control group. **P < 0.05 vs. I/R control group.