Figure 1 .

Clinical scores (CS) for individual pigs. A CS was assigned to each animal based on 4 FMD-relevant parameters: 1) Well-being: 0 = normal, 1 = depressed; 2) appetite: 0 = normal, 1 = suppressed; 3) mobility: 0 = free movement, 1 = lame, 2 = recumbent; 4) lesions on mouth/nose/tongue/feet (all 4 feet individually scored): 0 = no lesion, 1 = elevated temperature in local area/congestion/healing vesicle, 2 = vesicle, 3 = ruptured vesicle/severe lesion, in total giving a score between 0 and 25. Inoculated pigs = filled symbols and solid lines, in-contact pigs = open symbols and dotted lines. † indicates death or euthanasia for welfare reasons. Panel A: Group 1 (O1K B64), panel B: Group 2 (O1K/A-TUR), panel C: Group 3 (O1K/O-UKG), panel D: Group 4 (O-UKG/34/2001).