Table 1.
Genotype distribution of PAI-1 polymorphism in SSNHL and controls
| Model | Genotype | Controls, n = 113 (Frequency) | SSNHL, n = 103 (Frequency) | OR | 95 % CI | χ2 | p value |
|---|---|---|---|---|---|---|---|
| Co-dominant |
4 G/5 G |
50 (44.2 %) |
63 (61.2 %) |
1 |
|
|
|
| |
4 G/4 G |
29 (25.7 %) |
24 (23.3 %) |
0.66 |
0.34 – 1.27 |
1.59 |
0.210 |
| |
5 G/5 G |
34 (30.1 %) |
16 (15.5 %) |
0.37 |
0.19 - 0.75 |
7.83 |
0.005 |
| Recessive | 4 G/4 G-4 G/5 G |
79 (69.9 %) |
87 (84.5 %) |
1 |
|
|
|
| 5 G/5 G | 34 (30.1 %) | 16 (15.5 %) | 0.43 | 0.22 - 0.83 | 6.42 | 0.011 |
SSNHL sudden sensorineural hearing loss; Odds ratios (OR) with 95 % confidence intervals (CI) and results (p values) of χ2 analysis (chi-square test) were calculated for genotype frequencies compared with control.