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. 2012 Aug 30;8(8):e1002896. doi: 10.1371/journal.ppat.1002896

Figure 4. Interactions in the HIV-1 CAN:CPSF6313–327 complex.

Figure 4

(A–D) Detailed views of the HIV-1 CAN:CPSF6313–327 interface. HIV-1 CAN is shown as grey cartoon, HIV-1 residues that bind CPSF6 are in green and CPSF6313–327 in yellow. Water molecules involved in water-mediated interactions in the complex are shown as cyan spheres. (A) Overview of the HIV-1 CAN:CPSF6313–327 interface, showing all interacting residues and intermolecular hydrogen-bonding interactions. Views of the close-ups shown in (B), (C) and (D) are indicated. (B–D) HIV-1 CAN α-helices are labeled to aid orientation. Interacting residues are labeled (CPSF6 in normal font; HIV-1 in italics).