Table 1. Pilot study under various conditions.
VGB Dose (mg/kg) | Light | Exposure (hours) | Mouse | Total eyes | Negative | Positive | Comment |
1000 | cycle | 24 | 2 | 4 | 4 | 0 | |
1000 | light | 24 | 4 | 8 | 8 | 0 | |
1000 | light | 12 | 1 | 2 | 2 | 0 | |
1000 | light | 6 | 1 | 2 | 2 | 0 | |
1000 | dark | 12 | 1 | 2 | 2 | 0 | |
1000 | dark | 6 | 1 | 2 | 2 | 0 | |
1500 | cycle | 24 | 2 | 4 | 3 | 1 | |
1500 | light | 24 | 2 | 4 | 3 | 1 | |
2000 | cycle | 24 | 2 | 4 | 3 | 1 | 1 died overnight |
2000 | light | 24 | 2 | 4 | 4 | 0 | 1 died overnight |
2000 | cycle | 12 | 1 | 2 | 2 | 0 | |
2000 | light | 12 | 1 | 2 | 2 | 0 | |
3000 | cycle | 24 | 1 | 2 | 2 | 0 | 1 died overnight |
3000 | light | 24 | 1 | 2 | 2 | 0 | 1 died overnight |
3000 | light | 12 | 2 | 4 | 3 | 1 | |
3000 | dark | 12 | 1 | 2 | 1 | 1 |