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Inflammatory cell infiltration is significantly decreased in CD47−/− mice subjected to renal IRI. Representative photomicrographs and quantitative analysis of kidney tissue sections stained by immunohistochemistry for (A) neutrophils and (B) macrophages (total cell number per 10 hpf for both parameters). Data shown are mean ± SD, n=8–10 per group. *P=0.001 and **P<0.05 CD47−/− after IRI versus WT after IRI. Original magnification, ×400.
