Figure 1.

Manual annotation of lncRNAs in the human genome. (A) How lncRNAs were subclassified based on intersection with protein-coding genes. Priority was assigned to protein-coding exonic intersect over intronic or overlapping. Then, in cases where multiple protein-coding transcripts could be chosen, the protein-coding transcript having the longest intersect with the lncRNA was considered the best partner over the others (see Methods). (B) Number of lncRNA transcripts per subcategory. (S) Same sense; (AS) antisense.