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. 2012 Sep;22(9):1790–1797. doi: 10.1101/gr.137323.112

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© 2012, Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported License), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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Figure 4. — TNFAIP3-associated SNV. (A) RegulomeDB results for rs117480515 which is likely a functional variant associated with systemic lupus erythematosus. (B) This SNV was the most likely to be functional in the associated region but might be missed in a standard study because it lies >20 kb downstream from its target. (C) An enlargement of the region around rs117480515 (red line) shows the overlap with a large number of functional elements (NFKB, purple; BCL, light blue; and DNase, green) as well as the motif for BCL.