. Author manuscript; available in PMC: 2013 Sep 1.

Published in final edited form as: Clin Chest Med. 2012 Jul 7;33(3):431–443. doi: 10.1016/j.ccm.2012.05.005

Table 1.

Significant asthma susceptibility GWAS variants from meta-analyses or replicated studies.

Gene(s)	Chromosomal region	Ethnic background(s)	References
ORMDL3/GSDML	17q21	All	Moffat 2007, 2010, Torgersen 2011
IL1RL1/IL18R1	2q11	All	Moffatt 2010, Torgerson 2011
TSLP	5q22	All	Moffatt 2010, Torgerson 2011, Hirota 2011
IL33	9p24	All	Moffatt 2010, Torgerson 2011
SMAD3	15q23	European	Moffatt 2010
RORA	15q22	European	Moffatt 2010
HLA-DQ/DR	6p21	All	Moffatt 2010, Li 2010, Hirota 2011, Noguchi 2011
IL13	5q31	European	Moffatt 2010, Li 2010
PYHIN1	1q23	African	Torgerson 2011