Table 2.

The human T cell development is altered in HTLV-1 infected HIS Rag2^{– / –}γc^{– / –} mice.

	Immature	DP	SP
Percent of human thymocytes in mock-infected animals
Early	18 (3–23)	45 (30–70)	38 (25–60)
Late	10 (5–20)	45 (35–60)	38 (26–58)
Percent of human thymocytes in HTLV-1-infected animals
Low PVL	20 (2–38)	58 (40–80)	20 (10–40)
High PVL	2 (0–4)	15 (0–38)	75 (50–95)

Composite data from mock-infected mice and from HTLV-1-infected mice sacrificed early (early and low PVL, respectively) and late (late and high PVL, respectively) after CD34⁺ cell transplantation. Data represent mean ± SD of percent of human CD45⁺ thymocytes that are CD4^–CD8^– and CD4ISP immature cells, DP cells, and SP cells in the thymus of mice.