Table 1.
NCEP ATP III (3) | The Endocrine Society 2010a | ||||
---|---|---|---|---|---|
Normal | <150 mg/dl | <1.7 mmol/liter | Normal | <150 mg/dl | <1.7 mmol/liter |
Borderline-high triglycerides | 150–199 mg/dl | 1.7–2.3 mmol/liter | Mild hypertriglyceridemia | 150–199 mg/dl | 1.7–2.3 mmol/liter |
High triglycerides | 200–499 mg/dl | 2.3–5.6 mmol/liter | Moderate hypertriglyceridemia | 200–999 mg/dl | 2.3–11.2 mmol/liter |
Very high triglycerides | ≥500 mg/dl | ≥5.6 mmol/liter | Severe hypertriglyceridemia | 1000–1999 mg/dl | 11.2–22.4 mmol/liter |
Very severe hypertriglyceridemia | ≥2000 mg/dl | ≥22.4 mmol/liter |
The criteria developed for the present guidelines focus on the ability to assess risk for premature CVD vs. risk for pancreatitis. The designations of mild and moderate hypertriglyceridemia correspond to the range of levels predominant in risk assessment for premature CVD, and this range includes the vast majority of subjects with hypertriglyceridemia. Severe hypertriglyceridemia carries a susceptibility for intermittent increases in levels above 2000 mg/dl and subsequent risk of pancreatitis; very severe hypertriglyceridemia is indicative of risk for pancreatitis. In addition, these levels suggest different etiologies. Presence of mild or moderate hypertriglyceridemia is commonly due to a dominant underlying cause in each patient, whereas severe or very severe hypertriglyceridemia is more likely due to several contributing factors.