Fig. 8.

In situ hybridization with PDGFRα and MBP probes using a BrdU treated mice sample. The number of MBP labeled cells was significantly reduced in both the cortex and corpus callosum of Emx1-cKO mice (b) (**P < 0.01), whereas the number of PDGFRα in Emx1-cKO mice was nearly the same as that of their littermate controls (a). The number of cells labeled with both MBP and BrdU was distinctly decreased in Emx1-cKO mice compared to littermate controls (d) (**P < 0.01). The number of cells labeled with both PDGFRα and BrdU in Emx1-cKO mice was similar to that of littermate controls (c)