TABLE 1.
Clinical characteristics of B-CLL patients
α4 integrin subunit expression was determined for each sample and is indicated as the percentage of positive cells. ND, not determined.
| Patient | Sex/Age (y) | Stagea | α4 (%) | CD38/ZAP70b | Ig status |
|---|---|---|---|---|---|
| 1 | F/67 | B/II | 71 | −/ND | ND |
| 2 | F/54 | B/II | 55 | −/ND | Unmutated |
| 3 | M/43 | A/0 | 29 | −/− | Mutated |
| 4 | M/81 | A/0 | 57 | −/ND | Mutated |
| 5 | M/56 | C/IV | 88 | −/− | Unmutated |
| 6 | M/58 | B/II | 48 | +/+ | Unmutated |
| 7 | M/67 | B/II | 20 | −/+ | Mutated |
| 8 | M/69 | C/IV | 37 | +/+ | ND |
| 9 | F/83 | C/IV | 74 | −/+ | Mutated |
| 10 | M/70 | B/II | 75 | +/+ | Unmutated |
| 11 | M/64 | A/I | 78 | −/− | Mutated |
| 12 | M/80 | A/I | 81 | −/+ | Unmutated |
| 13 | M/77 | B/I | 82 | +/+ | ND |
| 14 | M/83 | B/I | 43 | +/+ | Unmutated |
| 15 | M/68 | B/II | 12 | −/+ | Mutated |
| 16 | M/59 | C/IV | 30 | +/+ | Unmutated |
| 17 | M/85 | C/IV | 25 | + / ND | Mutated |
| 18 | F/73 | A/II | 76 | −/− | Mutated |
| 19 | M/60 | A/0 | 37 | +/− | Mutated |
| 20 | M/48 | B/I | 20 | +/− | ND |