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Key residues identified in previous studies (57), mapped in the proposed three-dimensional structure of hMATE1. Purple, His; yellow, Cys; dark red, Glu. The side view is canted slightly to emphasize the position of these residues. N and C indicate the position of the N and C termini of the model, respectively. Note that the cytoplasmic location of the C terminus reflects the absence of the 13th TMH in this homology model.
