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. 2012 Aug 10;13(8):9980–9991. doi: 10.3390/ijms13089980

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© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Correlation between downregulated PTEN expression in hepatocellular carcinoma and histological grade. (a) Scatterplot showing PTEN levels determined by immunohistochemistry in hepatocellular carcinoma and adjacent non-neoplastic tissues; (b) downregulation of PTEN expression was significantly correlated with histological grade (p = 0.043, comparing histological grade I–II versus III). HCC, hepatocellular carcinoma; Normal, adjacent non-neoplastic tissue; IHC, immunohistochemistry.