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Schematic diagram of Transforming growth factor-beta-induced protein (βig-H3) protein structure. Secretory signal (SP) in the N-terminal cysteine rich domain (CRD), and four fasciclin-1 domains (FAS1 1–4). Position of several known integrin binding motifs, including NKDIL, YH18, EPDIM and Arg-Gly-Asp (RGD), are indicated.
