Figure 5.

Strain background has a greater influence on open-field activity than does TTA expression. a, Open-field analysis revealed significant differences between strains in the total distance traveled over the 30 min trial but no significant effect of TTA expression within any strain background (n = 10–14 per genotype per strain). b, On average, each group of mice spent between 20 and 30% of their distance traveled in the central third of the arena, with no significant difference between strains. Furthermore, in all strain backgrounds, expression of TTA had no effect on percentage path in center.