FIGURE 1:

The ADAM12L protein interaction network. The list of the 14 proteins that physically bind ADAM12L (Table 1) was used as input in the STRING application, and the graph was generated using default parameters. The interactions between ADAM12 and PRKCE (Sundberg et al., 2004), PRKCD (Asakura et al., 2002), GNB2L1 (Bourd-Boittin et al., 2008), and TGFBR2 (Atfi et al., 2007) and between TGFBR2 and Src (Galliher and Schiemann, 2007) have not been entered in the database yet and were added manually (green connecting lines).