Table 2.

Gradient effect of age interval by quartiles and frequency of risk factors using the Mantel–Haenszel test of linear trend

	Age (years)
	≤54.0	54.0–61.9	62.0–74.9	≥75.0	Total
Minority
Yes	62	48	28	9	147
No	112	126	172	178	588
Total	174	174	200	187	735
Frequency (%)	35.6	27.5	14.0	4.8	20.0
ORa (95% CI)	1.00	0.69 (0.43–1.11)	0.29 (0.17–0.50)	0.09 (0.04–0.20)
Current smoker
Yes	115	85	59	24	283
No	59	89	141	163	452
Total	174	174	200	187	735
Frequency (%)	66.1	48.8	29.5	12.8	38.5
ORb (95% CI)	1.0	0.49 (0.31–0.77)	0.21 (0.14–0.34)	0.08 (0.04–0.13)
Male sex
Yes	150	146	145	101	542
No	24	28	55	86	193
Total	174	174	200	187	735
Frequency (%)	86.0	83.0	72.5	54.0	73.7
ORc (95% CI)	1.00	0.83 (0.44–1.57)	0.42 (0.24–0.74)	0.19 (0.11–0.32)
History of hypertension
Yes	34	65	89	88	276
No	146	109	111	99	459
Total	174	174	200	187	735
Frequency (%)	19.5	37.1	44.5	47.0	37.6
ORd (95% CI)	1.00	2.56 (1.54–4.28)	3.44 (2.11–5.64)	3.82 (2.32–6.29)
Type 2 diabetes mellitus
Yes	19	25	41	27	112
No	155	149	159	160	623
Total	174	174	200	187	735
Frequency (%)	10.9	14.3	20.5	14.4	15.2
ORe (95% CI)	1.00	1.37 (0.69–2.71)	2.10 (1.13–3.95)	1.38 (0.70–2.70)

Notes:

^aChi square of linear trend: 63.608, df = 1, P value < 0.0001;

^bchi square of linear trend: 122.417, df = 1, P value < 0.0001;

^cchi square of linear trend: 54.734, df = 1, P value < 0.0001;

^dchi square of linear trend: 33.015, df = 1, P value < 0.0001;

^echi square of linear trend: 1.936, df = 1, P value = 0.1641.

Abbreviations: CI, confidence interval; df, degrees of freedom; OR, odds ratio.