Table 1. Glomerular Protein Expression in Fibronectin Glomerulopathy.

Protein	Fibronectin Glomerulopathy/N1	G2	Diabetic Nephropathy/N	G	Lupus Nephritis IV/N	G	Lupus Nephritis V/N	G
Matrix Proteins
Fibronectin 1	14	665
Fibronectin 3	14	663
Fibronectin 8	14	668
Fibronectin 14	14	66
Fibulin 1	53	44
Fibulin 1D	76	67
Fibulin 5	16.6	13.8
Laminin α-5	0.5	25
Heparan sulfate proteoglycan Core Protein	2	19	3	35			1.5	5
Complement System
C1q	13	7			20	12
C3	4.4	33	37	39	10	109	13	120
C4B	4.2	15	7	19			10	44
C5	18	12	30	13	22	14	67	41
C8							13	5.5
C9					2.4	5.7	5	23.5
Factor H	10	5
Serum Proteins
APOE	12	7	30	13			31	17
Amyloid P	4.6	10	9	19			4.8	8
Transthyretin	12	7
Fibrinogen α-chain	26	39	47	46	35	49	45	54
Fibrinogen β-chain	40	32	62	30	56	41	67	41
Podocyte Proteins
Podocin	0.06	15	0.4	7	0.14	9.4	0.17	7
Synaptopodin	0.13	43	.3	13	0.35	16.6
A-actinin	0.7	14	0.7	8
Complement Receptor 1 Isoform F Precursor	0.06	15	0.1	7	0.07	15	0.09	9
Neprilysin	0.16	41	0.14	26	0.21	30	0.34	15
Tight Junction Protein ZO-1	0.24	22	0.09	24	0.2	22	0.27	14
MYH9	0.65	33
Anti-Oxidant Proteins
Peroxiredoxin-5	0.18	6
Peroxiredoxin-6	0.07	12	.12	6	0.08	9.8	0.10	7.5
Glutathione S-transferase A1	0.1	7			0.12	5.6
Glutathione S-transferase A2	0.1	8			6	0.11

¹Ratio of normalized spectral counts of a protein found in a glomerular disease to the normalized spectral counts of the protein in control glomeruli

²G=G score, an estimate of significance if ≥5; if <5 spectral count ratio not given