Table 1. Tissue-specific expression profile of the TetO-H2B-GFP transgene under control of the original MMTV-tTA(NIH) strain and two novel MMTV-tTA transgenic lines (25754, 25755).
Line NIH | Line 25754 | Line 25755 | |
Mammary epithelial cells | * | *** | *** |
Salivary Gland (epithelial cells) | *** | *** | *** |
Thymus | *** | No | No |
Skin | *** | No | No |
Spleen | *** | No | No |
Pancreas | ** | No | No |
Liver | ** | No | No |
Kidney | * | No | No |
Heart | * | No | No |
Lung | * | No | No |
Intestine | No | No | No |
Skeletal muscle | No | No | No |
high;
moderate;
low H2B-GFP expression efficiency; No; the tTA-mediated expression of H2B-GFP was undetectable.