Table 2. Neutralization potential of plasma antibodies from HIV-1 patients against subtype-B and C tier 2 viruses.
AIIMS ID | Subtype | cAIIMS201 | cZM53M.PB12 | cDu156.12 | bRHPA4259.7 | bTRO.11 | cAIIMS212 | bJRFL | cZM109F.PB4 |
AIIMS206 | ND | >20000 | 17766 | 3016 | 3313 | 4199 | 4022 | 3040 | 3243 |
AIIMS213 | C | 1978 | 258 | 1940 | <60 | <60 | <60 | <60 | <60 |
AIIMS239 | C | 783 | 1257 | 317 | 509 | 385 | 457 | 245 | 220 |
AIIMS220 | ND | 106 | 480 | 2178 | 796 | 156 | <60 | 66 | 84 |
AIIMS914 | ND | 2264 | 431 | <60 | 119 | 163 | <60 | 445 | 113 |
AIIMS905 | ND | 2264 | <60 | <60 | 70 | 269 | <60 | 145 | <60 |
AIIMS249 | ND | 457 | 369 | 189 | 120 | 734 | 520 | 291 | 189 |
AIIMS210 | C | 1794 | <60 | 102 | <60 | <60 | <60 | 442 | <60 |
AIIMS232 | C | 210 | 440 | 510 | 214 | <60 | 316 | 244 | <60 |
AIIMS211 | ND | 68 | <60 | 222 | 1396 | <60 | 124 | <60 | <60 |
AIIMS225 | C | 208 | 90 | 1128 | 96 | <60 | 62 | <60 | <60 |
AIIMS901 | ND | 208 | 183 | 291 | <60 | 472 | 177 | 308 | <60 |
AIIMS287 | C | <60 | 838 | 302 | <60 | <60 | <60 | 264 | <60 |
AIIMS288 | ND | <60 | 752 | 108 | <60 | <60 | <60 | 76 | <60 |
AIIMS904 | ND | 618 | 235 | <60 | <60 | <60 | <60 | 76 | <60 |
AIIMS254 | C | 70 | <60 | 206 | 446 | 162 | <60 | <60 | 104 |
AIIMS289 | ND | <60 | 138 | 352 | 210 | <60 | <60 | 124 | 88 |
AIIMS212 | C | <60 | <60 | <60 | 656 | <60 | <60 | <60 | <60 |
AIIMS248 | ND | 226 | 88 | 298 | <60 | 108 | 88 | <60 | <60 |
AIIMS284 | ND | <60 | 334 | 250 | <60 | <60 | <60 | <60 | 78 |
AIIMS906 | ND | 418 | 70 | 62 | <60 | 142 | <60 | <60 | <60 |
AIIMS911 | ND | <60 | 72 | <60 | <60 | <60 | <60 | 463 | <60 |
AIIMS909 | ND | 405 | <60 | <60 | <60 | 89 | 85 | 75 | <60 |
AIIMS250 | ND | 110 | 160 | 230 | <60 | <60 | 84 | <60 | <60 |
AIIMS291 | ND | <60 | 292 | 84 | <60 | <60 | <60 | <60 | 116 |
AIIMS219 | ND | <60 | <60 | <60 | 366 | <60 | <60 | <60 | <60 |
AIIMS299 | ND | 108 | 74 | <60 | 78 | <60 | <60 | 66 | 264 |
AIIMS234 | C | <60 | <60 | 190 | <60 | <60 | 182 | <60 | <60 |
AIIMS255 | C | 146 | 90 | <60 | <60 | <60 | 168 | <60 | 64 |
AIIMS913 | ND | <60 | 281 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS300 | ND | 158 | <60 | <60 | 112 | <60 | <60 | <60 | 98 |
AIIMS281 | A | <60 | <60 | <60 | <60 | <60 | 98 | 204 | <60 |
AIIMS283 | ND | <60 | 228 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS264 | C | 78 | <60 | 204 | <60 | <60 | <60 | <60 | <60 |
AIIMS910 | ND | 68 | 209 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS205 | ND | <60 | 202 | 66 | <60 | <60 | <60 | <60 | <60 |
AIIMS242 | ND | <60 | 170 | 64 | <60 | 64 | 82 | <60 | <60 |
AIIMS274 | ND | <60 | 74 | 126 | <60 | 100 | <60 | <60 | 78 |
AIIMS277 | ND | <60 | <60 | 80 | 152 | <60 | <60 | 86 | <60 |
AIIMS290 | C | <60 | 184 | <60 | <60 | <60 | <60 | <60 | 72 |
AIIMS276 | ND | <60 | 148 | 82 | <60 | <60 | <60 | 62 | <60 |
AIIMS224 | C | <60 | <60 | 160 | <60 | <60 | <60 | <60 | <60 |
AIIMS208 | C | <60 | <60 | 156 | <60 | <60 | <60 | <60 | <60 |
AIIMS241 | C | 72 | <60 | 136 | <60 | <60 | 64 | <60 | <60 |
AIIMS253 | C | 120 | <60 | <60 | <60 | <60 | 88 | <60 | <60 |
AIIMS297 | ND | 80 | 66 | <60 | <60 | <60 | 110 | <60 | <60 |
AIIMS275 | C | <60 | <60 | 82 | <60 | <60 | <60 | <60 | 100 |
AIIMS230 | ND | <60 | <60 | 120 | <60 | <60 | <60 | <60 | <60 |
AIIMS286 | ND | <60 | <60 | <60 | <60 | <60 | 62 | 110 | <60 |
AIIMS273 | ND | <60 | 76 | <60 | 92 | <60 | <60 | <60 | <60 |
AIIMS235 | A | 82 | <60 | <60 | <60 | <60 | 84 | <60 | <60 |
AIIMS294 | C | <60 | <60 | <60 | 70 | <60 | <60 | 94 | <60 |
AIIMS203 | ND | <60 | <60 | 94 | <60 | <60 | <60 | <60 | <60 |
AIIMS908 | ND | <60 | <60 | <60 | <60 | 94 | <60 | <60 | <60 |
AIIMS293 | C | <60 | <60 | <60 | <60 | <60 | <60 | <60 | 86 |
AIIMS231 | ND | <60 | <60 | <60 | <60 | 74 | 68 | <60 | <60 |
AIIMS226 | C | <60 | <60 | <60 | <60 | <60 | 78 | <60 | <60 |
AIIMS272 | ND | <60 | 76 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS216 | ND | <60 | <60 | 70 | <60 | <60 | <60 | <60 | <60 |
AIIMS285 | ND | <60 | 70 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS271 | ND | <60 | <60 | <60 | <60 | <60 | <60 | 68 | <60 |
AIIMS298 | C | 66 | 62 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS233 | ND | <60 | <60 | 66 | <60 | <60 | <60 | <60 | <60 |
AIIMS915 | ND | 65 | 61 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS207 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS218 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS223 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS237 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS244 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS270 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS279 | A | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS280 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS282 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS292 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS295 | C | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS296 | C | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS902 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS903 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS907 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
AIIMS912 | ND | <60 | <60 | <60 | <60 | <60 | <60 | <60 | <60 |
The cross neutralizing activities of plasma antibodies from 80 HIV-1 infected drug naïve individuals from north India against the tier 2 subtype-B and C viruses indicated on the top of the table. Each virus is designated with its subtype (subtype-C and subtype-B; superscript alphabet on left). The AIIMS ID of the patient samples is given on the left of the table followed by the subtype of viruses they were infected with (C- subtype-C, A- subtype-A and ND- not determined). The numerical values in boxes are the 50% neutralization titers (ID50) defined as the dilution of plasma which neutralized 50% of viral infection in the assay. For clarity, this information is coded: ID50>1000 (Bold), ID50 = 61–1000 (Italic) and <60, where ID50 was not reached. Each experiment was performed at least two independent times.