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. 2012 Aug 31;7(8):e44230. doi: 10.1371/journal.pone.0044230

Figure 3. Motor coordination was assessed using the footprint, rotating rod, and hind-limb extension tests.

Figure 3

The footprint test was used to examine the walking pattern (A, B). The tottering-6j strain including 6j/6j (n = 15), 6j/+ (n = 15), and +/+ mice (n = 15), and the rolling Nagoya strain including rol/rol (n = 15), rol/+ (n = 15), and +/+ mice (n = 15) were used (A). The heterozygous mice including 6j/rol (n = 15), 6j/+ (n = 15), rol/+ (n = 15), and +/+ (n = 15) mice were used (B). In the rotating rod test, retention time on the rotating rod was examined in 6j/6j (n = 10), 6j/+ (n = 10), and +/+ mice (n = 10) (C). In the hind-limb extension test, hind-limb posture was scored as 2, 1, or 0 (D), and the score for each strain is presented (E) for 6j/6j (n = 10), 6j/+ (n = 10), and +/+ mice (n = 10). **P<0.001 compared to the appropriate control (Tukey's test).