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. 2012 Aug 31;7(8):e44089. doi: 10.1371/journal.pone.0044089

Figure 3. Phox2b-Cre-mediated GHSR re-expression fails to normalize ghrelin-stimulated feeding but restores fasting glucose levels.

Figure 3

Ghrelin (2 µg/g s.c.) potently induces 2-hr food intake when compared to saline injection in wild-type but not in GHSR-null mice or in GHSR null/Phox2b cre mice. (n = 7, * = P<0.05 One-way ANOVA with Tukey’s post-hoc test) (A). Hindbrain-selective GHSR expression restores fasting blood glucose to that of wild type. (n = 25, * = P<0.05 1-way ANOVA with Tukey’s post-hoc test C).