Table 2. Mass spectrometry results of retinal differential proteins between rd12 and C57BL/6J mice at age P14 and P21.
Group ID | Protein | Acc.no. | Theoretical | No.of matched peptides | Coverage (%) | Protein Score | |
MW (kDa) | PI | ||||||
1 | adipo Q ↑ | gi|1399498 | 26.83 | 5.3 | 5 | 24.41 | 37 |
2 | UNC-119 homolog ↑ | gi|6755939 | 26.99 | 5.81 | 24 | 81.24 | 767 |
3 | dihydropyrimidinase-like 3 isoform 2 ↑ | gi|6681219 | 61.9 | 6.04 | 22 | 50.96 | 395 |
4 | dynein cytoplasmic 1 intermediate chain 2 ↑ | gi|6753658 | 68.35 | 5.16 | 13 | 58.81 | 242 |
5 | PR264/SC35 ↑ | gi|1405747 | 13.97 | 10.24 | 12 | 66.38 | 275 |
6 | unnamed protein product ↑ | gi|26327249 | 29.7 | 5.15 | 14 | 27.88 | 218 |
7 | similar to splicing factor,arginine/serine-rich 3 ↑ | gi|224084730 | 14.2 | 10.12 | 13 | 64.24 | 292 |
8 | unnamed protein product ↓ | gi|12846244 | 17.97 | 8.44 | 7 | 72.52 | 422 |
9 | voltage-dependent anion channel 1 ↓ | gi|6755963 | 30.74 | 8.62 | 9 | 7.09 | 97 |
10 | platelet-activating factor acetylhydrolase ↓ | gi|6679201 | 25.84 | 6.42 | 13 | 89.24 | 338 |
11 | Wbscr1 alternative spliced product ↓ | gi|4972951 | 25.17 | 7.79 | 7 | 70.63 | 228 |
13 | unnamed protein product ↑ | gi|26329075 | 47.02 | 4.68 | 11 | 72.02 | 430 |
14 | endoplasmic reticulum protein ERp29 precursor ↓ | gi|19526463 | 28.81 | 5.9 | 8 | 22.37 | 197 |
15 | cytosolic malate dehydrogenase ↑ | gi|387129 | 36.45 | 6.16 | 14 | 73.3 | 608 |
16 | keratin 15 ↑ | gi|226823220 | 49.46 | 4.79 | 28 | 80.67 | 669 |
17 | unnamed protein product ↑ | gi|12833697 | 32.8 | 4.64 | 21 | 47.21 | 355 |
18 | alpha-tropomyosin ↑ | gi|157787199 | 32.66 | 4.69 | 29 | 42.98 | 425 |
19 | ribosomal protein, large P2 ↓ | gi|83745120 | 11.64 | 4.42 | 8 | 59.48 | 540 |
20 | phosphoprotein enriched in astrocytes 15 isoform 2 ↑ | gi|21426847 | 15.04 | 4.94 | 7 | 51.22 | 315 |
Note: ↑: the protein level is up-regulated in the untreated rd12 retinas; ↓: the protein level is down-regulated in the untreated rd12 retinas.