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. 2012 Aug 31;7(8):e44855. doi: 10.1371/journal.pone.0044855

Table 2. Mass spectrometry results of retinal differential proteins between rd12 and C57BL/6J mice at age P14 and P21.

Group ID Protein Acc.no. Theoretical No.of matched peptides Coverage (%) Protein Score
MW (kDa) PI
1 adipo Q ↑ gi|1399498 26.83 5.3 5 24.41 37
2 UNC-119 homolog ↑ gi|6755939 26.99 5.81 24 81.24 767
3 dihydropyrimidinase-like 3 isoform 2 ↑ gi|6681219 61.9 6.04 22 50.96 395
4 dynein cytoplasmic 1 intermediate chain 2 ↑ gi|6753658 68.35 5.16 13 58.81 242
5 PR264/SC35 ↑ gi|1405747 13.97 10.24 12 66.38 275
6 unnamed protein product ↑ gi|26327249 29.7 5.15 14 27.88 218
7 similar to splicing factor,arginine/serine-rich 3 ↑ gi|224084730 14.2 10.12 13 64.24 292
8 unnamed protein product ↓ gi|12846244 17.97 8.44 7 72.52 422
9 voltage-dependent anion channel 1 ↓ gi|6755963 30.74 8.62 9 7.09 97
10 platelet-activating factor acetylhydrolase ↓ gi|6679201 25.84 6.42 13 89.24 338
11 Wbscr1 alternative spliced product ↓ gi|4972951 25.17 7.79 7 70.63 228
13 unnamed protein product ↑ gi|26329075 47.02 4.68 11 72.02 430
14 endoplasmic reticulum protein ERp29 precursor ↓ gi|19526463 28.81 5.9 8 22.37 197
15 cytosolic malate dehydrogenase ↑ gi|387129 36.45 6.16 14 73.3 608
16 keratin 15 ↑ gi|226823220 49.46 4.79 28 80.67 669
17 unnamed protein product ↑ gi|12833697 32.8 4.64 21 47.21 355
18 alpha-tropomyosin ↑ gi|157787199 32.66 4.69 29 42.98 425
19 ribosomal protein, large P2 ↓ gi|83745120 11.64 4.42 8 59.48 540
20 phosphoprotein enriched in astrocytes 15 isoform 2 ↑ gi|21426847 15.04 4.94 7 51.22 315

Note: ↑: the protein level is up-regulated in the untreated rd12 retinas; ↓: the protein level is down-regulated in the untreated rd12 retinas.