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. 2012 Aug 31;7(8):e44855. doi: 10.1371/journal.pone.0044855

Table 3. Mass spectrometry results of retinal differential proteins between wide-type C57BL/6J, untreated rd12 and treated rd12 eyes at age P42.

Group ID Protein Acc.no. Theoretical No.of matched peptides Coverage (%) Protein Score
MW (kDa) PI
21 peroxiredoxin 6 ↑ gi|6671549 24.81 5.98 16 89.78 777
22 crystallin, alpha A ↑ gi|30794510 22.48 6.35 15 72.68 395
23 crystallin, beta A4 ↑ gi|10946672 22.45 5.9 13 78.39 586
24 crystallin, beta A1 ↑ gi|20304089 25.19 5.98 19 86.31 593
25 crystallin, beta A1 ↑ gi|20304089 25.19 5.98 15 79.92 570
26 ribosomal protein, large P2 ↑ gi|83745120 11.64 4.42 9 58.13 484
27 Heat shock protein 70 ↑ gi|42542422 70.83 5.28 33 79.74 674
28 hypothetical protein LOC433182 ↑ gi|70794816 47.11 6.37 29 59.92 726
29 crystallin, beta A1 ↑ gi|20304089 25.19 5.98 16 85.66 475
30 eukaryotic translation elongation factor 1 delta isoform b ↑ gi|54287684 31.27 4.96 11 30.94 212
31 unnamed protein product ↑ gi|26328639 17.82 9.41 11 61.51 409
32 fascin homolog 1, actin bundling protein * gi|113680348 54.47 6.44 26 35.72 321
33 peroxiredoxin 6 * gi|6671549 24.81 5.98 24 89.54 837
34 modifier 2 ↑ gi|53165 19.74 4.96 13 72.23 571
35 alpha-A-crystallin ↑ gi|387134 18.53 5.86 16 75.91 499
36 L-lactate dehydrogenase B * gi|6678674 36.55 5.7 13 52.44 311
37 Spna2 protein * gi|20380003 156.1 5.29 17 17.88 52
38 Spna2 protein * gi|20380003 156.1 5.29 45 43.65 259
39 retinol binding protein 1, cellular * gi|6755300 15.84 5.1 14 86.17 494
40 RecName: Full = Inosine-5′- monophosphate dehydrogenase 1; Short = IMP dehydrogenase 1; AltName: Full = IM # gi|1708472 55.26 6.29 23 56.13 541
41 crystallin, beta A2 # gi|10946978 22.22 6.3 12 73.53 617
42 eukaryotic translation initiation factor 6 # gi|27501448 26.49 4.63 5 22.4 264

Note: ↑: the protein is up-regulated in the untreated rd12 retinas; *: the protein is up-regulated in the treated rd12 retinas; #: the protein is up-regulated in the C57BL/6J retinas.