Table 1. Proliferation index (percentage of S+G₂M cells) of different BM cell compartments in MDS vs. both AML and normal/reactive BM.

BM cell compartment	Proliferation index of BM cell populations
	Normal/reactive BM (N = 94)	P-value †	MDS (N = 106)	P-value ¥	AML (N = 30)	P-value *
Whole BM	7% (1–17.5%)	<0.001	9% (2–27%)	0.008	7% (0.3–17%)	NS
Non-lymphoid CD34+ precursors	15% (6–28%)	0.05	13% (0.6–36%)	<0.001	6% (0.07–19%)	<0.001
Maturing neutrophils	5% (0.5–12%)	<0.001	7% (2–26%)	NS	7% (0.3–17%)	0.02
CD13hi/CD11b − cells	21% (4–37%)	0.01	19% (6–51%)	NS	17.5% (2–54%)	NS
CD13lo/int/CD11b − cells	21% (12–36%)	NS	21% (5–46%)	NS	17% (3–41%)	NS
CD13lo/int/CD11b+ cells	4 (0.8–12%)	0.002	5% (1–23%)	NS	7% (1–43%)	0.001
CD13hi/CD11b+ cells	0.5% (0.1–4%)	<0.001	2% (0.3–12%)	0.007	2% (0.2–36%)	<0.001
Monocytic cells	4.5% (0.1–21%)	NS	4% (0–16%)	NS	7% (0–10%)	NS
Nucleated red blood cell precursors	28% (11–45%)	NS	26% (2–48%)	0.01	21% (2–37%)	<0.001
Eosinophils	4% (0–13%)	0.01	7% (0–21%)	NS	5.5% (1.5–16%)	NS

Results expressed as median percentage of S+G₂/M cells and range between brackets. AML, acute myeloid leukemia; MDS, myelodysplastic syndrome; BM, bone marrow; NS, statistically not significantly different;

^†, MDS vs. normal/reactive BM;

^¥, MDS vs. AML;

^*, AML vs. normal/reactive BM.