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. 2012 Aug 31;7(8):e44426. doi: 10.1371/journal.pone.0044426

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© 2012 Gao et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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CaMKII-IR was localized in almost all VIP-immunoreactive neurons (A) and some ChAT-immunoreactive neurons (B) in rat submucosal plexus. In the mouse submucosal plexus, CaMKII-IR also colocalized extensively with VIP-IR (C) but much less with ChAT-IR (D). On the other hand, CaMKII-IR colocalized with both VIP-IR (E) and ChAT-IR (F) in human submucosal plexus. Yellow color refers to overlapping images. Bar = 20 μm for all images.