Figure 2. Intranasal instillations of manganese chloride reduce the number of nerve-shock evoked synaptic responses.

(A) Plot showing the number of nerve-shock evoked glomerular responses is reduced on the manganese-exposed side compared to the vehicle-exposed side. (B–C) Pseudocolored response maps and showing single nerve-shock evoked spH signals scaled to the maximum of the response in C. Call outs show individual traces of fluorescence change in corresponding glomerulus before and after stimulation, as indicated by arrow. The white outline indicates electrode location. ** indicates p < 0.001. The white scale bar denotes 200 μm. (D) Cumulative distribution of nerve shock evoked glomerular response amplitudes in vehicle- and manganese-exposed bulbs.