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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Gene Ther. 2012 Jan 12;19(12):1166–1176. doi: 10.1038/gt.2011.200

Figure 5.

Figure 5

Humoral immune response to hFVIII and AAVrh10 capsid in hemophilic mice injected on the second day of life. Neonatal mice received intravenously either saline or AAVrh10-FVIII expressing HC and LC. A) At 1, 3, 6, 9, and 12 months mice were bled and plasma was analyzed for antibodies to FVIII (n = 8 animals per group). B) At 1 month mice were bled and plasma was analyzed for antibodies to rh10 capsid protein. (n=6 animals per group) (* p=ns). (Error bars represent mean + SD)