Table 3. Long-term changes in plasma values in non-diabetic and diabetic patients following BPD-DS surgery.
| Variables |
Non-diabetic women n=32 |
Diabetic women n=22 |
||||||
|---|---|---|---|---|---|---|---|---|
| Pre-operative | 6 months | 12 months | P-value | Pre-operative | 6 months | 12 months | P-value | |
| BMI (kg m−2) | 48.6±7.4 | 35.8±6.2* | 29.5±6.2* | <0.001 | 49.8±8 | 37.2±6.6* | 32±5.6* | <0.001 |
| Fat mass (kg) | 66.9±13.5 | 40.5±11.3* | 28.1±11.1* | <0.001 | 66.2±14.9 | 39.6±11.1* | 29.9±9.7* | <0.001 |
| Lean mass (kg) | 59.3±8 | 52.4±7.2* | 50.3±6* | <0.001 | 61±9.5 | 55.1±9.3* | 50.9±9.2* | <0.001 |
| Fat percentage (%) | 52.8±2.6 | 43±5.3* | 34.8±7.4* | <0.001 | 51.7±3.6 | 41.4±5.9* | 36.5±7.1* | <0.001 |
| TG (mmol l−1) | 1.38±0.57 | 1.17±0.35* | 0.98±0.4* | <0.001 | 1.81±0.82 | 1.6±0.81 | 1.34±0.34* | <0.05 |
| Apo-B (mmol l−1) | 0.79±0.16 | 0.57±0.1* | 0.48±0.09* | <0.001 | 0.75±0.2 | 0.67±0.31 | 0.61±0.17 | NS |
| NEFA (mmol l−1) | 0.55±0.12 | 0.51±0.17 | 0.52±0.17 | NS | 0.53±0.17 | 0.64±0.24 | 0.58±0.24 | NS |
| Chol (mmol l−1) | 4.8±0.68 | 3.26±0.59* | 3.24±0.55* | <0.001 | 4.53±1.04 | 3.58±0.97* | 3.66±0.72* | <0.001 |
| HDL-Chol (mmol l−1) | 1.4±0.3 | 1.06±0.28* | 1.26±0.29* | <0.001 | 1.26±0.35 | 0.98±0.29* | 1.09±0.25* | <0.001 |
| LDL-Chol (mmol l−1) | 2.78±0.59 | 1.66±0.4* | 1.54±0.37* | <0.001 | 2.45±0.77 | 1.87±0.81* | 1.96±0.65* | <0.001 |
| Fructosamine (umol l−1) | 202±5.0 | 189±3.6 | 197±2.5 | NS | 230±9.9 | 203±5.1 | 201±4.0 | NS |
| hsCRP (g l−1) | 10.1±1.5 | 4.0±0.9 | 1.6±0.3 | NS | 10.8±1.7 | 6.4±1.6 | 2.5±0.5 | NS |
Abbreviations; BMI, body mass index; Chol, cholesterol; hsCRP, high sensitivity C-reactive protein; NEFA, non-esterified fatty acid; TG, triglyceride. The values are presented as mean±s.d. and significant differences were analyzed by repeated measures ANOVA followed by Holm–Sidak post-hoc test (*P<0.05) vs preoperative state.