Table 4. Meta-regression of NAA levels in the mPFC.
| Modifier | Separate dataset | Intercept | Slope | P-value |
|---|---|---|---|---|
| Y-BOCS | ||||
| Total | 10 | 1.94 | −0.10 | 0.011 |
| Obsession | 5 | −0.51 | −0.09 | 0.245 |
| Compulsion | 5 | −0.33 | −0.02 | 0.797 |
| % Of patients with depression | 10 | −0.20 | −2.00 | 0.259 |
| % Of patients with anxiety | 10 | −0.24 | −1.36 | 0.696 |
| Duration of illness | 9 | −0.22 | −0.01 | 0.742 |
| Age (years) | 10 | 0.11 | −0.02 | 0.297 |
| Size of VOI | 10 | −0.28 | −0.01 | 0.783 |
Abbreviations: mPFC, medial prefrontal cortex; NAA, N-acetylaspartate; VOI, volume of interest;Y-BOCS, Yale–Brown Obsessive Compulsive Scale.