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. 2012 Aug 28;2(8):e155. doi: 10.1038/tp.2012.83

Figure 4.

Figure 4

Social behavior characterization of juvenile naltrexone (NTRX) postnatally treated mice. (a) SAL mice significantly prefer the chamber of the apparatus characterized by the presence of a same sex/age partner, contrary to NTRX mice that did not discriminate between the two end chambers. Sociability index: 100 × time in social chamber/(time in social chamber + time in non-social chamber). Sample size: NTRX-♀=9, NTRX-♂=9, SAL-♀=7, SAL-♂=9. (b) SAL mice significantly preferred the social-cued chambers of a place preference apparatus, after a 10-day period of conditioning, contrary to NTRX mice showing no preference between compartments. Conditioned Social Place Preference protocol (CSPP) index=100 × time social-cued chamber/(time social-cued chamber +time-isolated cued chamber). Sample size: SAL-♀=7, SAL-♂=5, NTRX-♀=6, NTRX-♂=6. **P<0.01.