Table 1.

Age of death (range, in years) per mutation; > means beyond the age of

Gene mutated	Range age of death (years)	Number of observations
NDUFAF1	0.6 – >24	2
NDUFAF2	0.8 – 13.5	9
NDUFAF3	0.2 – 0.3	4
NDUFAF4	0 – 1,5	9
ACAD9	0.1 – >12	7
FOXRED1	>10 - > 22	2
NUBPL	>8	1
C20orf7	0 – >29	8
C8orf38	> 1,8 – 2.9	2
NDUFA1	1.2 – >38	5
NDUFA2	0.9	1
NDUFA10	1.9	1
NDUFA11	0 – 4	5
NDUFA12	> 10	1
NDUFS1	0.4 – >4	10
NDUFS2	0.3 – >17	15
NDUFS3	13	1
NDUFS4	0.3 – 2,3	14
NDUFS6	0	6
NDUFS7	0.5 – 5	6
NDUFS8	0.2 – >9	3
NDUFV1	0.3 – >13	17
NDUFV2	0.2	1