Table 2.

IHC scoring systems

	Score
	0	1+	2	3
Yi et al. [46]	No staining	Faint cytoplasmic staining	Moderate smooth cytoplasmic staining	Intense granular cytoplasmic staining in ≥10 % of tumour cells
Kim et al. [27]	No staining	Faint or weak staining intensity with >5 % tumour cells or any staining intensity with ≤5 % tumour cells a	Moderate staining intensity with >5 % tumour cells b	Strong and granular staining intensity with >5 % tumour cells c

^aAverage of 14.7 % positively stained cells

^bAverage of 58.2 % positively stained cells

^cAverage of 97.3 % positively stained cells