Figure 3.

Expression of GV sPLA₂ in saline and Ang II–infused apoE^−/− mouse hearts. A: Real-time RT-PCR showing increased mRNA abundance in apoE^−/− hearts after 3 days of Ang II infusion. B: IHC analysis of heart sections from an apoE^−/− mouse infused with saline or Ang II for 7 days. GV sPLA₂ (red fluorescence) and SMC α-actin (green fluorescence) are visualized by confocal microscopy. Arrows indicate smooth muscle cells, and asterisks indicate cardyomyocytes. Original magnification, ×40. C: GV sPLA₂ is not detected in the GV DKO mouse heart.