Table 1.
Characteristics of the study population.
| Variable | Cases | Control subjects |
|---|---|---|
| N (%)* | N (%)* | |
| Age | ||
| <30 | 147 (10) | 129 (9) |
| 30–39 | 147 (10) | 153 (11) |
| 40–49 | 175 (12) | 183 (13) |
| 50–59 | 269 (19) | 274 (19) |
| 60–69 | 390 (28) | 397 (27) |
| =70 | 286 (21) | 311 (21) |
| Study Centre | ||
| Spain | 301 (21) | 318 (22) |
| France | 149 (11) | 152 (10) |
| Germany | 518 (37) | 530 (37) |
| Italy | 106 (7) | 110 (8) |
| Ireland | 105 (7) | 102 (7) |
| Czech Republic | 235 (17) | 235 (16) |
| Sex | ||
| Male | 787 (56) | 802 (55) |
| Female | 627 (44) | 645 (45) |
| Lymphoma subtype | ||
| Hodgkin lymphoma (HL) | 259 (18) | - |
| T-cell lymphoma (T-NHL) | 90 (6) | - |
| B-cell lymphoma (B-NHL) | 1114 (76) | - |
| Diffuse large B-cell lymphoma (DLBCL) | 391 (28) | - |
| Follicular lymphoma (FL) | 195 (14) | - |
| Chronic lymphocytic leukaemia (CLL) | 321 (23) | - |
| Mantle cell lymphoma (MCL) | 48 (3) | - |
| Marginal zone B-cell lymphoma (MZL) | 110 (8) | - |
| Removed samples† | 67 | 44 |
| 1481 | 1491 |
*
Percentage is based on the final population used for statistical analysis.
†
65 cases and 44 controls were removed due to low performance of the genotyping (call-rate below 0.95); additionally, 2 cases were excluded due to missing information on age.