Figure 8.

Dependence of the number of IP₃R's that participate of a signal on various parameters. Mean (symbols) and standard deviations (vertical lines around mean) of the number of IP₃R's that participate of a signal, N_o, as a function of the inter-cluster distance, dm (A), of the mean number of IP₃-bound IP₃R's per cluster, λ (B), of the mean IP₃R inhibition time, t_inh (C), and of the cytosolic Ca²⁺ clearing rate, δ_Ca (D). In all the subfigures, the parameters that are not varied are fixed at the values used in section 5.